circRNA basic information
circBase ID: -
Name: hsa_circ_ZFR
Synonym: circ-ZFR
Host Gene: hsa-miR-212-5p
 
 
 
Disease basic information
DO ID:
 2394
DO name: ovarian cancer
Disease details: ovarian cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: OC cell line (A2780)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-212-5p
Biological function: Repressive circ-ZFR constraints OC cell advancement with glycolysis
Molecular mechanism: Circ-ZFR negatively modulates hsa-miR-212-5p.hsa-miR-212-5p targets SOD2
Survival: -
Supported No.:
 1
Description:

In short, Pro restrained glycolysis via mediating the circ-ZFR/miR-212-5p/SOD2 axis. These results offered a better theoretical foundation for comprehending the molecular pathology of OC and provided a novel target for OC diagnosis and treatment.
Other information
Title:

Propofol modulates glycolysis reprogramming of ovarian tumor via restraining circular RNA-zinc finger RNA-binding protein/microRNA-212-5p/superoxide dismutase 2 axis.

Journal: Bioengineered
Published: 2022/5/12
PubMed ID: 35543376