circRNA basic information
circBase ID: hsa_circ_0093887
Name: -
Synonym: circ_0093887
Host Gene: hsa-miR-758-3p
 
 
 
Disease basic information
DO ID:
 1936
DO name: atherosclerosis
Disease details: atherosclerosis
Species: human
Species details: human
Sample type: cell line
Sample type details: ox-LDL-induced HAECs
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: BAMBI
Associated microRNA: hsa-miR-758-3p
Biological function: Overexpression of circ_0093887 promoted HAECs viability and tube formation, and restrained cell apoptosis in ox-LDL-induced HAECs compared with untreated HAECs.
Molecular mechanism: circ_0093887 regulated the expression of BAMBI through miR-758-3p.
Survival: -
Supported No.:
 2
Description:

Circ_0093887 demonstrated its diagnostic and therapeutic value in AS by promoting the role of the miR-758-3p/BAMBI axis in the ox-LDL-induced endothelial injury of HAECs.
Other information
Title:

Circ_0093887 regulated ox-LDL induced human aortic endothelial cells viability, apoptosis, and inflammation through modulating miR-758-3p/BAMBI axis in atherosclerosis.

Journal: Clin Hemorheol Microcirc
Published: 2022/5/10
PubMed ID: 35527543