circRNA basic information
circBase ID: -
Name: hsa_circ_MEMO1
Synonym: circ-MEMO1
Host Gene: hsa-miR-485-3p
 
 
 
Disease basic information
DO ID:
 3910
DO name: lung adenocarcinoma
Disease details: lung adenocarcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human LUAD cell lines (A549, H522), normal human bronchial epithelial cell line (BEAS-2B)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-485-3p
Biological function: circ-MEMO1 and NEK4 expression in LUAD cells could be suppressed,
Molecular mechanism: circ-MEMO1 acted as a sponge for hsa-miR-485-3p to modulate the expression of hsa-miR-485-3p-targeted oncogene NEK4.
Survival: poor
Supported No.:
 1
Description:

Promoting the circ-MEMO1-miR-485-3p-NEK4 axis might halt the tumor-inhibiting role of propofol in LUAD cells in vitro, suggesting a potential epigenetic pathway of propofol.
Other information
Title:

Anesthetic propofol suppresses growth and metastasis of lung adenocarcinoma in vitro through downregulating circ-MEMO1-miR-485-3p-NEK4 ceRNA axis.

Journal: Histol Histopathol
Published: 2022/5/7
PubMed ID: 35521898