circRNA basic information
circBase ID: -
Name: hsa_circ_OMA1
Synonym: circOMA1
Host Gene: hsa-miR-1294
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human osteoblast (hFOB1.19), OS cell lines
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-1294
Biological function: Silencing circOMA1 suppressed osteosarcoma progression_n vitro_nd_n vivo.
Molecular mechanism: circOMA1 functioned as a sponge of hsa-miR-1294 to upregulate c-Myc expression.
Survival: -
Supported No.:
 4
Description:

circOMA1 played the role of an oncogene in osteosarcoma and promoted osteosarcoma progression by mediating the miR-1294/c-Myc pathway, which might be a new target for treating osteosarcoma.
Other information
Title:

Silencing circOMA1 Inhibits Osteosarcoma Progression by Sponging miR-1294 to Regulate c-Myc Expression.

Journal: Front Oncol
Published: 2022/5/3
PubMed ID: 35493998