circRNA basic information
circBase ID: -
Name: hsa_circ_CDK13
Synonym: circCDK13
Host Gene: hsa-miR-17-5p
 
 
 
Disease basic information
DO ID:
 409
DO name: liver disease
Disease details: liver fibrosis
Species: human
Species details: human
Sample type: cell line
Sample type details: human bone marrow mesenchymal stem cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-17-5p
Biological function: hMSCs-derived exosomes inhibited liver fibrosis mainly through circCDK13.
Molecular mechanism: Exo-circCDK13 inhibited PI3K/AKT and NF-¦ĘB signaling pathways activation through regulating the hsa-miR-17-5p/KAT2B axis.
Survival: -
Supported No.:
 1
Description:

hMSCs-derived exosome circCDK13 inhibited liver fibrosis by regulating the expression of MFGE8 through miR-17-5p/KAT2B axis.
Other information
Title:

hMSCs-derived exosome circCDK13 inhibits liver fibrosis by regulating the expression of MFGE8 through miR-17-5p/KAT2B.

Journal: Cell Biol Toxicol
Published: 2022/4/29
PubMed ID: 35484432