circRNA basic information
circBase ID: -
Name: hsa_circ_TRHDE
Synonym: circTRHDE
Host Gene: hsa-miR-318-3p
 
 
 
Disease basic information
DO ID:
 552
DO name: pneumonia
Disease details: pneumonia
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: WI-38 cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TRAF3
Associated microRNA: hsa-miR-318-3p
Biological function: knockdown of circTRHDE remitted LPS-triggered WI-38 cell injury.
Molecular mechanism: CircTRHDE could sponge miR-381-3p to positively regulate TRAF3 expression.
Survival: -
Supported No.:
 2
Description:

Our findings demonstrated that circTRHDE might be a target for infantile pneumonia treatment, which relieved LPS-induced cell inflammatory injury by the regulation of the miR-318-3p/TRAF3 axis.
Other information
Title:

CircTRHDE knockdown protects WI-38 cells against LPS-induced inflammatory injury.

Journal: Autoimmunity
Published: 2022/4/29
PubMed ID: 35481453