circRNA basic information
circBase ID: hsa_circ_0004788
Name: -
Synonym: circ_0004788
Host Gene: hsa-miR-515-5p
 
 
 
Disease basic information
DO ID:
 9261
DO name: nasopharynx carcinoma
Disease details: nasopharyngeal carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: NPC cells (5-8F, C666-1; OBiotech, Shenzhen, China), human nasopharyngeal epithelial cells (NP69; OBiotech)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DS
Associated gene: -
Associated microRNA: hsa-miR-515-5p
Biological function: The impacts of circ_0004788 knockdown on cell progression in NPC cells were reversed by miR-515-5p inhibitor, and FGF2 overexpression could block the suppressive effect of miR-515-5p on cell progression in NPC cells.
Molecular mechanism: The impacts of circ_0004788 knockdown on cell progression in NPC cells were reversed by hsa-miR-515-5p inhibitor, and FGF2 overexpression could block the suppressive effect of hsa-miR-515-5p on cell progression in NPC cells.
Survival: -
Supported No.:
 1
Description:

Circ_0004788 knockdown restrained the progression of NPC via the miR-515-5p/FGF2 axis.
Other information
Title:

Identification of the regulatory role of the circ_0004788/miR-515-5p/FGF2 network in nasopharyngeal carcinoma development.

Journal: Head Neck
Published: 2022/4/24
PubMed ID: 35460538