circRNA basic information
circBase ID: -
Name: hsa_circ_Snrk
Synonym: circ-Snrk
Host Gene: -
 
 
 
Disease basic information
DO ID:
 3021
DO name: acute kidney failure
Disease details: acute kidney injury
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: NRK-52E cells
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: MAPK
Associated microRNA: -
Biological function: Circ-Snrk knockdown inhibited apoptosis of NRK-52E cells and secretion of inflammatory factors (IL-6 and TNF-¦Á).
Molecular mechanism: circ-Snrk knockdown could inhibit the activation of p-JNK and p-38 transcription factors.
Survival: -
Supported No.:
 1
Description:

Circ-Snrk is involved in AKI development and associated with the MAPK signaling pathway in AKI.
Other information
Title:

Inhibition of Circ-Snrk ameliorates apoptosis and inflammation in acute kidney injury by regulating the MAPK pathway.

Journal: Ren Fail
Published: 2022/4/14
PubMed ID: 35416113