circRNA basic information
circBase ID: hsa_circ_0051620
Name: -
Synonym: circ_0051620
Host Gene: hsa-miR-338-3p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: GC cell lines (AGS, HGC27, MKN-45, MKN74), human gastric mucosal epithelial cell line (GES-1)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-338-3p
Biological function: everall overexpression of miR-338-3p inhibited the cell migration, invasion through inhibiting ADAM17 in GC cells.
Molecular mechanism: hsa-miR-338-3p was confirmed to be the target of circ_0051620.
Survival: -
Supported No.:
 1
Description:

The overexpression of circ_0051620 is found to be associated with progress and poor prognosis of GC, promoting the development and metastasis via sponging miR-338-3p and decoying ADAM17.
Other information
Title:

Circular RNA circ_0051620 sponges miR-338-3p and regulates ADAM17 to promote the gastric cancer progression.

Journal: Pathol Res Pract
Published: 2022/4/13
PubMed ID: 35413598