circRNA basic information
circBase ID: hsa_circ_0058129
Name: hsa_circ_FN1
Synonym: circ_0058129
Host Gene: hsa-miR-873-5p
 
 
 
Disease basic information
DO ID:
 1781
DO name: thyroid gland cancer
Disease details: thyroid cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: papillary thyroid cancer cell lines (TPC_1, SNU_790)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: follistatin-like
Associated microRNA: hsa-miR-873-5p
Biological function: The circ_0058129 and FSTL1 abundances were increased, while the miR-873-5p content was decreased in PTC tissues and cells compared with control groups. Circ_0058129 shortage inhibited PTC cell proliferation, migration, and invasion.
Molecular mechanism: miR-873-5p repressed PTC cell malignancy by binding to FSTL1. Circ_0058129 targeted hsa-miR-873-5p to regulate FSTL1.
Survival: -
Supported No.:
 1
Description:

Circ_0058129 expedited PTC progression through the miR-873-5p/FSTL1 pathway.
Other information
Title:

Hsa_circ_0058129 regulates papillary thyroid cancer development via miR-873-5p/follistatin-like 1 axis.

Journal: J Clin Lab Anal
Published: 2022/4/5
PubMed ID: 35373391