circRNA basic information
circBase ID: hsa_circ_0047744
Name: -
Synonym: circ_0047744
Host Gene: hsa-miR-21
 
 
 
Disease basic information
DO ID:
 3498
DO name: pancreatic ductal adenocarcinoma
Disease details: pancreatic ductal adenocarcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human normal pancreatic ductal epithelial cells (HPDE6-c7), human pancreatic cancer cell lines (PANC-1, MiaPaCa-2)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: SOCS5
Associated microRNA: hsa-miR-21
Biological function: -
Molecular mechanism: -
Survival: poor
Supported No.:
 1
Description:

Circ_0047744 acts as an anti-oncogene to inhibit PDAC metastasis by regulating the miR-21/SOCS5 axis, indicating that circ_0047744 may be a potential novel therapeutic target for PDAC patients.
Other information
Title:

Circular RNA circ_0047744 suppresses the metastasis of pancreatic ductal adenocarcinoma by regulating the miR-21/SOCS5 axis.

Journal: Biochem Biophys Res Commun
Published: 2022/3/26
PubMed ID: 35334414