circRNA basic information
circBase ID: -
Name: -
Synonym: novel_circ_0004830
Host Gene: bta-miR-145
 
 
 
Disease basic information
DO ID:
 10690
DO name: mastitis
Disease details: mastitis
Species: cow
Species details: cow
Sample type: cell line
Sample type details: MAC-T bovine mammary epithelial cell line (a cell model of cow mastitis)
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DN
Associated gene: TRAF6, IL-6, IL-8, TNFalpha
Associated microRNA: bta-miR-145
Biological function: the regulation of the mammary inflammatory response
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

Interestingly, novel_circ_0004830 and novel_circ_0003097 may both act as ceRNAs and bind to bta-miR-145. Chen et al. (2019) revealed that bta-miR-145 regulates Staphylococcus aureus (S. aureus)-induced mastitis in MAC-T cells by targeting the FSCN1 gene.
Other information
Title:

Differential expression of circRNAs related to lipopolysaccharide-induced inflammation in bovine mammary epithelial cells.

Journal: Res Vet Sci
Published: 2022/3/20
PubMed ID: 35305362