circRNA basic information
circBase ID: -
Name: ebv_circ_RPMS1
Synonym: ebv-circRPMS1
Host Gene: -
 
 
 
Disease basic information
DO ID:
 5517
DO name: stomach carcinoma
Disease details: gastric carcinoma
Species: others
Species details: virus
Sample type: cell line
Sample type details: EBV-positive gastric cell line (SNU719), EBV-negative gastric cell lines (BGC823, SGC7901, AGS), HEK-293T cells.
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: Sam68, METTL3
Associated microRNA: -
Biological function: We observed high ebv-circRPMS1 expression in EBVaGC and showed that ebv-circRPMS1 promoted the proliferation, migration, and invasion and inhibited the apoptosis of EBVaGC cells.
Molecular mechanism: ebv-circRPMS1/Sam68/METTL3 axis
Survival: -
Supported No.:
 1
Description:

ebv-circRPMS1, Sam68, and METTL3 might serve as therapeutic targets for EBVaGC.
Other information
Title:

ebv-circRPMS1 promotes the progression of EBV-associated gastric carcinoma via Sam68-dependent activation of METTL3.

Journal: Cancer Lett
Published: 2022/3/20
PubMed ID: 35304258