circRNA basic information
circBase ID: -
Name: hsa_circ_PSEN1
Synonym: circPSEN1
Host Gene: -
 
 
 
Disease basic information
DO ID:
 10652
DO name: Alzheimer disease
Disease details: Alzheimer disease
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

Our findings show the differential expression of circPSEN1 is increased in ADAD. Given the biological function previously ascribed to circular RNAs and the results of our in-silico analyses, we hypothesize that this finding might be related to neuroinflammatory events that lead or that are caused by the accumulation of amyloid-beta.
Other information
Title:

Circular RNA detection identifies circPSEN1 alterations in brain specific to autosomal dominant Alzheimer disease.

Journal: Acta Neuropathol Commun
Published: 2022/3/6
PubMed ID: 35246267