circRNA basic information
circBase ID: hsa_circ_0016760
Name: -
Synonym: Circ_0016760
Host Gene: hsa-miR-876-3p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: BEAS-2B, A549, H1975 , H1299and H460
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-876-3p
Biological function: Circ_0016760 depletion suppressed NSCLC cell proliferation and metastasis in vitro, as well as hampered tumor growth in vivo.
Molecular mechanism: Circ_0016760 acted as a sponge of hsa-miR-876-3p, and hsa-miR-876-3p could target NOVA2.
Survival: -
Supported No.:
 6
Description:

Circ_0016760 could promote the malignant development of NSCLC through miR-876-3p/NOVA2 axis, at least in part.
Other information
Title:

Circ_0016760 Serves as a Cancer Promoter in Non-small Cell Lung Cancer Through miR-876-3p/NOVA2 Axis.

Journal: Biochem Genet
Published: 2022/3/4
PubMed ID: 35239092