circRNA basic information
circBase ID: -
Name: -
Synonym: F-circEA-2a
Host Gene: hsa-miR-3940-5p
 
 
 
Disease basic information
DO ID:
 3717
DO name: gastric adenocarcinoma
Disease details: gastric adenocarcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HGC-27, MKN-45
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-3940-5p
Biological function: F-circEA-2a promoted GA cell proliferation and inhibited the role of miR-3940-5p in reducing cell proliferation.
Molecular mechanism: F-circEA-2a suppressed hsa-miR-3940-5p maturation in GA cells. hsa-miR-3940-5p directly bound to F-circEA-2a wild type (-wt), but not mutant (-mut).
Survival: -
Supported No.:
 1
Description:

Our study characterized a novel circRNA regulating miR-3940-5p maturation in GA.
Other information
Title:

Circular RNA F-circEA-2a expression is increased in gastric adenocarcinoma and inhibits the transition from premature microRNA-3940-5p to mature microRNA-3940-5p.

Journal: Bioengineered
Published: 2022/3/3
PubMed ID: 35235752