circRNA basic information
circBase ID: -
Name: hsa_circ_WHSC1
Synonym: CircWHSC1
Host Gene: hsa-miR-532-3p
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: a normal cervical epithelial cell line (Ect1/E6E7), CaCx cell lines (HeLa, CaSki, SiHa)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-532-3p
Biological function: CircWHSC1 silencing was capable of suppressing the proliferation, metastasis, and invasion of tumor cells and inducing apoptosis.
Molecular mechanism: circWHSC1 functioned as a competitive endogenous RNA (ceRNA), mediating LTBP2 expression by targeting hsa-miR-532-3p.
Survival: -
Supported No.:
 1
Description:

The circWHSC1-mediated miR-532-3p/LTBP2 signaling axis might be a novel therapeutic target for CaCx.
Other information
Title:

CircWHSC1 expedites cervical cancer progression via miR-532-3p/LTBP2 axis.

Journal: Mol Cell Biochem
Published: 2022/3/3
PubMed ID: 35235125