circRNA basic information
circBase ID: hsa_circ_0089153
Name: -
Synonym: circ_0089153
Host Gene: hsa-miR-2467-3p
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: BT-549, MDA-MB-231 cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-2467-3p
Biological function: circ_0089153 knockdown attenuated BCa cells proliferation, migration, invasion and epithelial-mesenchymal transition (EMT)
Molecular mechanism: circ_0089153 was hsa-miR-2467-3p sponge.E2F6 was directly suppressed by hsa-miR-2467-3p.
Survival: poor
Supported No.:
 1
Description:

circ_0089153 was an oncogene in breast cancer, which enhanced proliferation and metastasis through sponging miR-2467-3p/E2F6. circ_0089153 was suggested to be a potential target for BCa target treatment.
Other information
Title:

circ_0089153 exacerbates breast cancer cells proliferation and metastasis via sponging miR-2467-3p/E2F6.

Journal: Environ Toxicol
Published: 2022/3/1
PubMed ID: 35225430