circRNA basic information
circBase ID: hsa_circ_0008035
Name: -
Synonym: Circ_0008035
Host Gene: hsa-miR-1256
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: cell line, PDX
Sample type details: human gastric mucosal epithelial cells (GES-1), GC cell lines (AGS, N87)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-1256
Biological function: Silencing of circ_0008035 reduced GC cell proliferation, migration, and invasion while enhancing apoptosis.
Molecular mechanism: hsa-miR-1256 was a target of circ_0008035. CEACAM6 was a target of hsa-miR-1256.
Survival: -
Supported No.:
 4
Description:

Collectively, circ_0008035 regulated the expression of CEACAM6 by sponging miR-1256, thereby promoting the development of GC. Our data provided a novel targeted therapy for GC.
Other information
Title:

Circ_0008035 promotes the progression of gastric cancer via the regulation of miR-1256/CEACAM6 axis.

Journal: Cell Cycle
Published: 2022/3/1
PubMed ID: 35220873