circRNA basic information
circBase ID: -
Name: hsa_circ_CYP24A1
Synonym: CircCYP24A1
Host Gene: hsa-miR-421
 
 
 
Disease basic information
DO ID:
 4451
DO name: renal carcinoma
Disease details: renal carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: 786-O, A498
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-421
Biological function: circCYP24A1 overexpression inhibited the proliferation, invasion, and migration of RCC cells.
Molecular mechanism: circCYP24A1 inhibited RCC progression by sponging hsa-miR-421, thus inducing CMTM-4 expression.
Survival: poor
Supported No.:
 1
Description:

Taken together, circCYP24A1 is a prognosis-related circRNA in RCC that functions through the circCYP24A1/miR-421/CMTM-4 axis to modulate RCC progression.
Other information
Title:

CircCYP24A1 hampered malignant phenotype of renal cancer carcinoma through modulating CMTM-4 expression via sponging miR-421.

Journal: Cell Death Dis
Published: 2022/2/28
PubMed ID: 35220395