circRNA basic information
circBase ID: -
Name: hsa_circ_MID1
Synonym: circMID1
Host Gene: hsa-miR-330-3p
 
 
 
Disease basic information
DO ID:
 10283
DO name: prostate cancer
Disease details: prostate cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human PCa cells (PC-3, DU145), normal prostate epithelial cells (RWPE-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-330-3p
Biological function: knockdown inhibited PCa cell proliferation, migration, invasion and glycolysis in vitro, as well as PCa tumorigenesis in vivo.
Molecular mechanism: circMID1 could sponge hsa-miR-330-3p and hsa-miR-330-3p could target IGF1R and YTHDC2.
Survival: -
Supported No.:
 2
Description:

In conclusion, our data confirmed that circMID1 might play a pro-cancer role in PCa, which promoted PCa progression through regulating the miR-330-3p/YTHDC2/IGF1R/AKT axis.
Other information
Title:

Circular RNA midline-1 (circMID1) promotes proliferation, migration, invasion and glycolysis in prostate cancer.

Journal: Bioengineered
Published: 2022/2/26
PubMed ID: 35212614