circRNA basic information
circBase ID: mmu_circ_0001295
Name: -
Synonym: mmu_circ_0001295
Host Gene: -
 
 
 
Disease basic information
DO ID:
 0040085
DO name: bacterial sepsis
Disease details: sepsis
Species: mouse
Species details: mouse
Sample type: PDX
Sample type details: -
circRNA-disease information
Detected method:
S
Detected method confidence Low
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: downregulation of exosomal mmu_circ_0001295 suppressed the exosomes protective effects against sepsis.
Molecular mechanism: HExo prevented microvascular dysfunction, thus potentially improving sepsis outcomes via mmu_circ_0001295 delivery.
Survival: -
Supported No.:
 1
Description:

In summary, the data indicated that HExo elongate sepsis-induced renal injury through delivering mmu_circ_0001295.
Other information
Title:

Circular RNA mmu_circ_0001295 from hypoxia pretreated adipose-derived mesenchymal stem cells (ADSCs) exosomes improves outcomes and inhibits sepsis-induced renal injury in a mouse model of sepsis.

Journal: Bioengineered
Published: 2022/2/26
PubMed ID: 35212606