circRNA basic information
circBase ID: -
Name: hsa_circ_EPS15
Synonym: circEPS15
Host Gene: -
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human HCC cell lines (BEL-7402, BEL-7404, Huh7, Hep3B, HepG2), normal hepatocyte cell line (HL-7702)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: The overexpression of circEPS15 suppressed tumor cell invasion and migration
Molecular mechanism: inhibiting the TJP1/CDH2/VIM signaling pathway and retarded cell cycle progression
Survival: poor
Supported No.:
 1
Description:

Collectively, our study reveals that endogenous circEPS15 plays a novel role in repressing HCC through the ceRNA network and encodes a functional protein.
Other information
Title:

circEPS15 Overexpression in Hepatocellular Carcinoma Modulates Tumor Invasion and Migration.

Journal: Front Genet
Published: 2022/2/26
PubMed ID: 35211158