circRNA basic information
circBase ID: hsa_circ_0030018
Name: -
Synonym: circ_0030018
Host Gene: hsa-miR-136
 
 
 
Disease basic information
DO ID:
 11612
DO name: polycystic ovary syndrome
Disease details: polycystic ovary syndrome
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: KGN, COV434, IOSE80 cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-136
Biological function: Knockdown of circ_0030018 suppressed the proliferation, migration, and invasion of cells, while promoting their apoptosis.
Molecular mechanism: circ_0030018 sponged hsa-miR-136, which targeted MIEN1
Survival: -
Supported No.:
 1
Description:

In summary, loss of circ_0030018 delayed the progression of PCOS via the miR-136/MIEN1 axis.
Other information
Title:

The circular RNA circ_0030018/miR-136/migration and invasion enhancer 1 (MIEN1) axis promotes the progression of polycystic ovary syndrome.

Journal: Bioengineered
Published: 2022/2/22
PubMed ID: 35184658