circRNA basic information
circBase ID: hsa_circ_0001955
Name: -
Synonym: Circ_0001955
Host Gene: hsa-miR-1299
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: MDA_MB_453, SKBR3, MCF_10A cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-1299
Biological function: Knockdown of circ_0001955 inhibited breast cancer cell proliferation, migration, invasion, angiogenesis and glycolysis.
Molecular mechanism: circ_0001955 targeted hsa-miR-1299 to positively regulate GLUT1 expression.
Survival: -
Supported No.:
 2
Description:

Circ_0001955 was found to promote breast cancer malignant development via targeting of the miR-1299/GLUT1 pathway, which contributes to our understanding of the pathogenesis of breast cancer.
Other information
Title:

Circ_0001955 plays a carcinogenic role in breast cancer via positively regulating GLUT1 via decoying miR-1299.

Journal: Thorac Cancer
Published: 2022/2/18
PubMed ID: 35174654