circRNA basic information
circBase ID: hsa_circ_0016347
Name: -
Synonym: Circ_0016347
Host Gene: hsa-miR-661
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human osteoblasts (hFOB), osteosarcoma cell lines (U2OS, SaoS-2, HOS)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-661
Biological function: The suppression of circ_0016347 impeded proliferation, migration, invasion, and cell cycle and induced apoptosis in osteosarcoma cells
Molecular mechanism: circ_0016347 could regulate IL6R expression through hsa-miR-661.
Survival: -
Supported No.:
 2
Description:

Circ_0016347 functioned as an oncogene in osteosarcoma at least in part by the miR-661/IL6R axis and JAK2/STAT3 signalling pathway.
Other information
Title:

Circ_0016347 modulates proliferation, migration, invasion, cell cycle, and apoptosis of osteosarcoma cells via the miR-661/IL6R axis.

Journal: Autoimmunity
Published: 2022/2/16
PubMed ID: 35166635