circRNA basic information
circBase ID: -
Name: hsa_circ_ORC5
Synonym: circORC5
Host Gene: hsa-miR-30c-2-3p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: normal gastric epithelial cell line (GES1), GC cell lines (SGC-7901, MKN-28, BGC-823, AGS, MGC-803)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: AKT1S1
Associated microRNA: hsa-miR-30c-2-3p
Biological function: -
Molecular mechanism: -
Survival: poor
Supported No.:
 1
Description:

Our findings demonstrate that METTL14-mediated m6A modification of circORC5 suppresses gastric cancer progression by regulating miR-30c-2-3p/AKT1S1 axis.
Other information
Title:

METTL14-mediated m(6)A modification of circORC5 suppresses gastric cancer progression by regulating miR-30c-2-3p/AKT1S1 axis.

Journal: Mol Cancer
Published: 2022/2/16
PubMed ID: 35164771