circRNA basic information
circBase ID: hsa_circ_0120175
Name: -
Synonym: Circ_0120175
Host Gene: hsa-miR-330-3p
 
 
 
Disease basic information
DO ID:
 2876
DO name: laryngeal squamous cell carcinoma
Disease details: laryngeal squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: LSCC cell lines (AMC-HN-8, TU686, FD-LSC-1, SNU-899), 16HBE
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-330-3p
Biological function: Circ_0120175 interference suppressed cell proliferation, migration and invasion and induced cell apoptosis of LSCC cells.
Molecular mechanism: Circ_0120175 could sponge and negatively regulate hsa-miR-330-3p expression in LSCC cells.SLC7A11 bound to hsa-miR-330-3p.
Survival: -
Supported No.:
 1
Description:

Circ_0120175 promoted proliferation, migration and invasion while impeded cell apoptosis of LSCC cells through miR-330-3p/SLC7A11 axis, which provided novel therapeutic targets for LSCC.
Other information
Title:

Circ_0120175 promotes laryngeal squamous cell carcinoma development through up-regulating SLC7A11 by sponging miR-330-3p.

Journal: J Mol Histol
Published: 2022/2/11
PubMed ID: 35142935