circRNA basic information
circBase ID: hsa_circ_0026579
Name: -
Synonym: Circ_0026579
Host Gene: hsa-miR-24-3p
 
 
 
Disease basic information
DO ID:
 10533
DO name: viral pneumonia
Disease details: infantile pneumonia
Species: human
Species details: human
Sample type: cell line
Sample type details: human embryonic lung fibroblast cells (WI-38
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-24-3p
Biological function: Circ_0026579 expression was promoted in LPS-induced WI-38 cells, and its knockdown alleviated LPS-induced WI-38 cells inflammation.
Molecular mechanism: hsa-miR-24-3p was sponged by circ_0026579. IGF2 was targeted by hsa-miR-24-3p
Survival: -
Supported No.:
 1
Description:

Circ_0026579 positively regulated IGF2 expression through sponging miR-24-3p. Circ_0026579 knockdown alleviated LPS-induced WI-38 cells inflammation by miR-24-3p/IGF2 axis, suggesting that circ_0026579 might contribute to infantile pneumonia progression.
Other information
Title:

Circ_0026579 alleviates LPS-induced WI-38 cells inflammation injury in infantile pneumonia.

Journal: Innate Immun
Published: 2022/2/11
PubMed ID: 35142578