circRNA basic information
circBase ID: -
Name: hsa_circ_ZNF609
Synonym: circ-ZNF609
Host Gene: hsa-miR-514a-5p
 
 
 
Disease basic information
DO ID:
 1781
DO name: thyroid gland cancer
Disease details: thyroid cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: TPC-1, IHH-4 cells.
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-514a-5p
Biological function: Circ-ZNF609 knockdown prevented the malignant biological behaviors of TPC-1 and IHH-4 cells.
Molecular mechanism: circ-ZNF609 sponged hsa-miR-514a-5p and hsa-miR-514a-5p knockdown reversed the suppressed impacts of circ-ZNF609 knockdown on TC cell malignant biological behaviors.
Survival: -
Supported No.:
 1
Description:

The findings highlighted the importance of circ-ZNF609 function in facilitating TC cell development and metastasis_n vitro_nd_n vivo_ia binding to miR-514a-5p.
Other information
Title:

CircRNA ZNF609 promotes the growth and metastasis of thyroid cancer in vivo and in vitro by downregulating miR-514a-5p.

Journal: Bioengineered
Published: 2022/2/10
PubMed ID: 35135416