circRNA basic information
circBase ID: hsa_circ_0039569
Name: hsa_circ_CCL22
Synonym: circ_0039569
Host Gene: hsa-miR-197
 
 
 
Disease basic information
DO ID:
 1380
DO name: endometrial cancer
Disease details: endometrial cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: Endometrial carcinoma cell lines (HEC-1-B, AN3-CA, KLE, HEC1-A, Ishikawa), hEEC (human endometrial endothelial cells)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-197
Biological function: hsa_circ_0039569 facilitated the proliferation, migration and invasion of endometrial carcinoma cells.
Molecular mechanism: he underlying mechanism is that hsa_circ_0039569 serves as a sponge of hsa-miR-197 to repress the inhibitory effect of hsa-miR-197 on HMGA1.
Survival: -
Supported No.:
 3
Description:

Collectively, hsa_circ_0039569 may promote the development of endometrial carcinoma by serving as an endogenous sponge of miR-197, increasing HMGA1 expression and identifying a novel target for endometrial carcinoma treatment.
Other information
Title:

Hsa_circ_0039569 facilitates the progression of endometrial carcinoma by targeting the miR-197/high mobility group protein A1 axis.

Journal: Bioengineered
Published: 2022/2/9
PubMed ID: 35130798