circRNA basic information
circBase ID: -
Name: -
Synonym: hsa_circRNA_012448
Host Gene: hsa-miR-29b-2-5p
 
 
 
Disease basic information
DO ID:
 557
DO name: kidney disease
Disease details: diabetic kidney disease
Species: human
Species details: human
Sample type: cell line
Sample type details: human proximal tubular epithelial cells (PTECs)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-29b-2-5p
Biological function: oxidative stress response,
Molecular mechanism: hsa_circRNA_012448-hsa-miR-29b-2-5p-GSK3beta pathway
Survival: -
Supported No.:
 1
Description:

our study provides novel insights into the molecular mechanisms underlying the effects of dapagliflozin on DKD.
Other information
Title:

Identification of circular RNAs and functional competing endogenous RNA networks in human proximal tubular epithelial cells treated with sodium-glucose cotransporter 2 inhibitor dapagliflozin in diabetic kidney disease.

Journal: Bioengineered
Published: 2022/2/8
PubMed ID: 35129424