circRNA basic information
circBase ID: hsa_circ_0002113
Name: hsa_circ_IFNGR2
Synonym: -
Host Gene: hsa-miR-188-3p
 
 
 
Disease basic information
DO ID:
 5844
DO name: myocardial infarction
Disease details: myocardial Infarction
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: H9C2 cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: RUNX1
Associated microRNA: hsa-miR-188-3p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

In conclusion, exosomes derived from circRNA_0002113 lacking MSCs could suppress myocardial infarction by sponging miR-188-3p to regulate RUNX1 nuclear translocation. The circRNA_0002113/miR-188-3p/RUNX1 axis mediated alleviation of apoptosis serves as a novel strategy to treat myocardial I/R injury.
Other information
Title:

Therapeutic Potential of Exosomes Derived From circRNA_0002113 Lacking Mesenchymal Stem Cells in Myocardial Infarction.

Journal: Front Cell Dev Biol
Published: 2022/2/8
PubMed ID: 35127703