circRNA basic information
circBase ID: hsa_circ_0065898
Name: hsa_circ_VPRBP
Synonym: -
Host Gene: hsa-miR-1200, hsa-miR-145, hsa-miR-1250, hsa-miR-1273d, hsa-miR-2277, hsa-miR-299
 
 
 
Disease basic information
DO ID:
4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: A CSCC cell line (SiHa)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: H2AFZ, ACTB, RLIM, UBE2K, SP1, GATA6, NCOA3, CALM1, FKBP1A, PPIA
Associated microRNA: hsa-miR-1200, hsa-miR-145, hsa-miR-1250, hsa-miR-1273d, hsa-miR-2277, hsa-miR-299
Biological function: promoted CSCC cell proliferation, migration, and invasion.
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
4
Description:

We demonstrated that hsa_circ_0065898 promoted CSCC cell proliferation, migration, and invasion. Hence, hsa_circ_0065898 might be useful as a biomarker for CSCC diagnosis and targeted therapy.

Other information
Title:

Identification of a novel circRNA, hsa_circ_0065898, that regulates tumor growth in cervical squamous cell carcinoma.

Journal: Transl Cancer Res
Published: 2022/2/5
PubMed ID: 35116238