circRNA basic information
circBase ID: hsa_circ_0072088
Name: -
Synonym: Circ_0072088
Host Gene: hsa-miR-944
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: NSCLC cell lines (A549, H1299)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-944
Biological function: circ_0072088 knockdown improved CDDP sensitivity and repressed NSCLC cell malignancy
Molecular mechanism: circ_0072088 functioned as a sponge for hsa-miR-944 and hsa-miR-944 targeted LASP1.
Survival: -
Supported No.:
 3
Description:

Circ_0072088 silencing improved CDDP sensitivity and inhibited NSCLC progression by downregulating LASP1 expression through sponging miR-944. These data provide novel insight into the resistance of NSCLC to CDDP.
Other information
Title:

Circ_0072088 knockdown contributes to cisplatin sensitivity and inhibits tumor progression by miR-944/LASP1 axis in non-small cell lung cancer.

Journal: J Gene Med
Published: 2022/2/3
PubMed ID: 35106879