circRNA basic information
circBase ID: -
Name: hsa_circ_CUL2
Synonym: Circ-CUL2
Host Gene: hsa-miR-888-5p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: Culture of human NSCLC cell lines (A549, NCI-H1299, PC-9, LLC), normal human liver cell line (BEAS-2B)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-888-5p
Biological function: Elevated Circ-CUL2 or refrained miR-888-5p repressed A549/DDP cell progression with depressive DDP resistance.
Molecular mechanism: circ-CUL2 curbed hsa-miR-888-5p, which targeted RB1CC1.
Survival: -
Supported No.:
 2
Description:

Circ-CUL2 is supposed to be a novel biomarker offering a brand-new strategy for NSCLC therapy.
Other information
Title:

Circ-CUL2/microRNA-888-5p/RB1CC1 axis participates in cisplatin resistance in NSCLC via repressing cell advancement.

Journal: Bioengineered
Published: 2022/1/25
PubMed ID: 35068326