circRNA basic information
circBase ID: -
Name: hsa_circ_SMOC1-2
Synonym: circSmoc1-2
Host Gene: hsa-miR-874-3p
 
 
 
Disease basic information
DO ID:
 178
DO name: vascular disease
Disease details: vascular calcification
Species: human
Species details: human
Sample type: cell line
Sample type details: rat VSMC cell line (A10)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: Adam19
Associated microRNA: hsa-miR-874-3p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

In conclusion, we revealed that the circSmoc1-2/miR-874-3p/Adam19 axis regulates VC, suggesting that circSmoc1-2 may be a novel therapeutic target in the treatment of VC.
Other information
Title:

Circular RNA circSmoc1-2 regulates vascular calcification by acting as a miR-874-3p sponge in vascular smooth muscle cells.

Journal: Mol Ther Nucleic Acids
Published: 2022/1/18
PubMed ID: 35036071