circRNA basic information
circBase ID: hsa_circ_0001955
Name: hsa_circ_CSNK1G1
Synonym: circ_0001955
Host Gene: hsa-miR-655-3p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human HCC cell lines (HCCLM3, SNU-387, MHCC97H, Huh-7), normal (THLE-2)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-655-3p
Biological function: circ_0001955 deletion suppressed HCC tumorigenesis_n vitro_y suppressing cell growth, metastasis and angiogenesis.
Molecular mechanism: circ_0001955 could competitively sponge hsa-miR-655-3p, which targeted ACER3.
Survival: -
Supported No.:
 5
Description:

This study suggested a novel circ_0001955/miR-655-3p/ACER3 pathway in HCC progression.
Other information
Title:

Circular RNA circ_0001955 promotes hepatocellular carcinoma tumorigenesis by up-regulating alkaline ceramidase 3 expression through microRNA-655-3p.

Journal: Bioengineered
Published: 2022/1/18
PubMed ID: 35034572