circRNA basic information
circBase ID: -
Name: hsa_circ_ITGA7
Synonym: circITGA7
Host Gene: hsa-miR-370-3p
 
 
 
Disease basic information
DO ID:
 10283
DO name: prostate cancer
Disease details: prostate cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human prostate cancer cell lines (DU145, LNCaP, PC3), normal human prostate epithelial cells (RWPE-1)
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-370-3p
Biological function: Gain- or loss-of-function assays showed that circITGA7 inhibited the proliferation of PCa cells_n vivo_nd_n vitro.
Molecular mechanism: circITGA7 served as a sponge for hsa-miR-370-3p, and hsa-miR-370-3p could target P21CIP1_n PCa cells.
Survival: -
Supported No.:
 1
Description:

our data indicated that circITGA7 played an important role in inhibiting tumor proliferation in PCa and might be a potential therapeutic target.
Other information
Title:

circITGA7 Acts as a miR-370-3p Sponge to Suppress the Proliferation of Prostate Cancer.

Journal: J Oncol
Published: 2022/1/11
PubMed ID: 35003259