circRNA basic information
circBase ID: -
Name: hsa_circ_N4BP2L2
Synonym: circN4BP2L2
Host Gene: -
 
 
 
Disease basic information
DO ID:
 2394
DO name: ovarian cancer
Disease details: ovarian cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human EOC cell lines (SKOV3, OVCAR3, CAOV3, HO8910, TOV-112D), human normal ovarian epithelial cell line (IOSE80)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: Decreased circN4BP2L2 was significantly associated with advanced tumor stage, worse histological grade, lymph node metastasis and distant metastasis in EOC. CircN4BP2L2 inhibited tumor cell migration and invasion in vitro.
Molecular mechanism: -
Survival: better
Supported No.:
 1
Description:

Plasma circN4BP2L2 is significantly downregulated in EOC and might serve as a promising novel diagnostic biomarker for EOC patients, especially in early stage EOC cases..
Other information
Title:

Plasma circN4BP2L2 is a promising novel diagnostic biomarker for epithelial ovarian cancer.

Journal: BMC Cancer
Published: 2022/1/5
PubMed ID: 34980005