circRNA basic information
circBase ID: hsa_circ_0007919
Name: -
Synonym: Circ_0007919
Host Gene: hsa-miR-942-5p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: normal human colonic epithelial cell line (NCM460), human CRC cell lines (HT29, SW480, HCT-116, LoVo)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-942-5p
Biological function: circ_0007919 overexpression markedly suppressed CRC cell growth and migration.
Molecular mechanism: circ_0007919 could competitively bind with hsa-miR-942-5p to increase the expression of hsa-miR-942-5ps target gene TET1.
Survival: -
Supported No.:
 1
Description:

circ_0007919 inhibits CRC cell growth and migration via regulating the miR-942-5p/TET1 axis. This study helps to better understand the molecular mechanism of CRC progression.
Other information
Title:

Circ_0007919 exerts an anti-tumor role in colorectal cancer through targeting miR-942-5p/TET1 axis.

Journal: Pathol Res Pract
Published: 2021/12/16
PubMed ID: 34906917