circRNA basic information
circBase ID: -
Name: hsa_circ_FOXM1
Synonym: CircFOXM1
Host Gene: hsa-miR-1179
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human HCC cell lines (Huh7, HepG2, Hep3B, HCCLM3, MHCC97-H), normal human hepatocytes (MIHA)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-1179
Biological function: CircFOXM1 promotes proliferation and metastasis of HCC cells in vitro, and HCC xenograft growth in vivo
Molecular mechanism: CircFOXM1 sponges hsa-miR-1179 in HCC cells to increase SPAG5 expression
Survival: poor
Supported No.:
 2
Description:

CircFOXM1 promoted HCC cell proliferation and metastasis by regulating miR-1179/SPAG5 axis.
Other information
Title:

CircFOXM1 promotes proliferation and metastasis of hepatocellular carcinoma via regulating miR-1179/SPAG5 axis.

Journal: Sci Rep
Published: 2021/12/15
PubMed ID: 34903799