circRNA basic information
circBase ID: hsa_circ_0001367
Name: -
Synonym: Circ_0001367
Host Gene: hsa-miR-545-3p
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: U87, LN229, U251, T98G
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: LUZP1
Associated microRNA: hsa-miR-545-3p
Biological function: Hsa_circ_0001367 Inhibits the Proliferation, Migration and Invasion of Glioma Cells
Molecular mechanism: Hsa_circ_0001367 Act as a Sponge of hsa-miR-545-3p,Hsa_circ_0001367 Suppresses Glioma Progression by Absorbing hsa-miR-545-3p,LUZP1 Is the Direct Target of hsa-miR-545-3p,LUZP1 Downregulation Restored the Effect of hsa-miR-545-3p Knockdown or circ_0001367 Overexpression on Glioma Cells
Survival: -
Supported No.:
 2
Description:

the results of this study demonstrate that the circ_0001367/miR-545-3p/LUZP1 axis may be a novel target for glioma therapy.
Other information
Title:

The Circ_0001367/miR-545-3p/LUZP1 Axis Regulates Cell Proliferation, Migration and Invasion in Glioma Cells.

Journal: Front Oncol
Published: 2021/12/7
PubMed ID: 34869035