circRNA basic information
circBase ID: hsa_circ_0062019
Name: -
Synonym: circ_0062019
Host Gene: hsa-miR-1253
 
 
 
Disease basic information
DO ID:
 10283
DO name: prostate cancer
Disease details: prostate cancer
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-1253
Biological function: Depletion of circ_0062019 curbed cell proliferation, migration, invasion, angiogenesis and EMT and induced apoptosis in PCa cells.
Molecular mechanism: Circ_0062019 facilitated the malignancy of PCa cells via sequestering hsa-miR-1253. Simultaneously, hsa-miR-1253 hindered PCa cell progression via regulating NRBP1. Ccirc_0062019 silencing suppressed tumour growth in vivo.
Survival: -
Supported No.:
 3
Description:

circ_0062019 expedited PCa progression through mediating miR-1253/NRBP1 pathway.
Other information
Title:

Circular RNA circ_0062019 exerts oncogenic properties in prostate cancer via mediating miR-1253/NRBP1 axis.

Journal: Andrologia
Published: 2021/12/7
PubMed ID: 34866220