circRNA basic information
circBase ID: hsa_circ_0000463
Name: hsa_circ_EP400NL
Synonym: Circ_0000463
Host Gene: hsa-miR-924
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: non_small cell lung cancer cell lines (NCI_H1299, HCC827, A549, H460), normal human bronchial epithelioid cell line (16HBE)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SLC1A5
Associated microRNA: hsa-miR-924
Biological function: Circ_0000463 absence suppresses the malignant behaviors of NSCLC cells,Circ_0000463 absence suppresses xenograft tumor growth in vivo
Molecular mechanism: Circ_0000463 silencing suppresses the glutamine metabolism of NSCLC cells by targeting miR_924/SLC1A5 axis
Survival: -
Supported No.:
 1
Description:

Circ_0000463 absence suppressed the malignant behaviors and glutamine metabolism of NSCLC cells through mediating miR_924/SLC1A5 axis.
Other information
Title:

Circ_0000463 contributes to the progression and glutamine metabolism of non-small-cell lung cancer by targeting miR-924/SLC1A5 signaling.

Journal: J Clin Lab Anal
Published: 2021/11/24
PubMed ID: 34811815