circRNA basic information
circBase ID: -
Name: -
Synonym: circRNA_103124
Host Gene: hsa-miR-650
 
 
 
Disease basic information
DO ID:
 8778
DO name: Crohn disease
Disease details: Crohn disease
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HEK293T cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: AKT2
Associated microRNA: hsa-miR-650
Biological function: The hsa-miR-650 Inhibitor Reversed the Inhibitory Effect of hsa_circRNA_103124 siRNA on Cell Proliferation
Molecular mechanism: Hsa_circRNA_103124 Targeted hsa-miR-650,Hsa_circRNA_103124 Targeted AKT2 by Sponging hsa-miR-650
Survival: -
Supported No.:
 1
Description:

These results indicate that hsa_circRNA_103124 upregulation in patients with CD promotes cell proliferation and inhibits autophagy by regulating the hsa-miR-650/AKT2 signaling pathway.
Other information
Title:

Hsa_circRNA_103124 Upregulation in Crohn Disease Promotes Cell Proliferation and Inhibits Autophagy by Regulating the Hsa-miR-650/AKT2 Signaling Pathway.

Journal: Front Genet
Published: 2021/11/23
PubMed ID: 34804121