circRNA basic information
circBase ID: -
Name: hsa_circ_ANTXR1
Synonym: CircANTXR1
Host Gene: hsa-miR-532-5p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: HCC cells (HuH-7, HCCLM3), human liver epithelial cell line (THLE-2)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: XRCC5
Associated microRNA: hsa-miR-532-5p
Biological function: CircANTXR1 Silencing Inhibited the Proliferation, Migration and Invasion of HCC Cells
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

CircANTXR1 promotes the progression of HCC through the miR-532-5p/XRCC5 axis, which might be a potential serum biomarker and therapeutic target of HCC.
Other information
Title:

CircANTXR1 Contributes to the Malignant Progression of Hepatocellular Carcinoma by Promoting Proliferation and Metastasis.

Journal: J Hepatocell Carcinoma
Published: 2021/11/18
PubMed ID: 34786378