circRNA basic information
circBase ID: -
Name: hsa_circ_PLEKHM3
Synonym: circ-PLEKHM3
Host Gene: hsa-miR-320a
 
 
 
Disease basic information
DO ID:
 2394
DO name: ovarian cancer
Disease details: ovarian cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: ovarian cancer cell lines (SKOV3, A2780), human embryonic kidney cells (293_T)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: SMG1
Associated microRNA: hsa-miR-320a
Biological function: Circ-PLEKHM3 overexpression exacerbated curcumin-mediated tumor growth suppression in ovarian cancer
Molecular mechanism: -
Survival: -
Supported No.:
 2
Description:

Curcumin restrained proliferation and facilitated apoptosis in ovarian cancer by regulating the circ-PLEKHM3/miR-320a/SMG1 axis.
Other information
Title:

Curcumin inhibits ovarian cancer progression by regulating circ-PLEKHM3/miR-320a/SMG1 axis.

Journal: J Ovarian Res
Published: 2021/11/18
PubMed ID: 34784955