circRNA basic information
circBase ID: -
Name: hsa_circ_IGF1R
Synonym: Circ-IGF1R
Host Gene: hsa-miR-194-5p
 
 
 
Disease basic information
DO ID:
 8893
DO name: psoriasis
Disease details: psoriasis
Species: human
Species details: human
Sample type: cell line
Sample type details: human keratinocyte cell line (HaCaT), 293T cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CDK1
Associated microRNA: hsa-miR-194-5p
Biological function: inhibits apoptosis
Molecular mechanism: proliferation, migration and invasion, and inhibited apoptosis
Survival: -
Supported No.:
 1
Description:

circ-IGF1R-siRNA could inhibit the cell proliferation, migration and invasion, and induce apoptosis by regulating the miR-194-5p/CDK1 axis. circ-IGF1R may thus serve as a potential treatment target for psoriasis.
Other information
Title:

Circ-IGF1R plays a significant role in psoriasis via regulation of a miR-194-5p/CDK1 axis.

Journal: Cytotechnology
Published: 2021/11/16
PubMed ID: 34776628