circRNA basic information
circBase ID: -
Name: hsa_circ_LOPD2
Synonym: circ-LOPD2
Host Gene: hsa-miR-378
 
 
 
Disease basic information
DO ID:
 2394
DO name: ovarian cancer
Disease details: ovarian cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-378
Biological function: After silencing circ-LOPD2, the growth ability of OVCAR3 and A2780 cells decreased, while overexpression of circ-LOPD2 led to the opposite result
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circ-LOPD2 as a miR-378 sponge promotes the proliferation of ovarian cancer cells, which may in turn promote the development of OC.
Other information
Title:

CircRNA PLOD2 enhances ovarian cancer propagation by controlling miR-378.

Journal: Saudi J Biol Sci
Published: 2021/11/12
PubMed ID: 34759745